LMGP - rubrique Laboratoire - Minatec 2022

Catherine Picart, Research Director at CEA Grenoble, Direction of Fundamental Research

  Catherine Picart, Research-Engineer at CEA Grenoble, Vice-Head of Department of Health, Direction of Fundamental Research 


  • 1994 : Master in Biomedical Engineering, Université Joseph Fourier, Grenoble, France.
  • 1994 : Engineering degree in physics of Materials, Grenoble Institute of Technology, France
  • 1997 : PhD in Biomedical Engineering, Université Joseph Fourier, Grenoble, France
  • 2002 : Habilitation to conduct research, University Louis Pasteur, Strasbourg, France






Biomaterials, Biophysics, Biomimetism, Tissue Engineering, Regenerative Medicine, Drug delivery



125 publications and 14 invited reviews in peer-reviewed journals such as PNAS, Adv. Mat., Biomaterials, Adv. Funct. Mat, Acta. Biomat., Small, Biophys. J., , Biomacromolecules, Langmuir, J. Cell Biol., J. Cell Sci.


  1. Liu, X-Q., and Picart, C. Layer-by-layer assemblies for cancer treatment and diagnosis. Adv. Mater. 28:1295-1301, 2016.
  2. Bouyer, M., Guillot, R., et al. Surface delivery of tunable doses from an adaptable polymeric scaffold induces volumetric bone regeneration. Biomaterials. 104. 168-81, 2016.
  3. Liu XQ et al, Biomaterial-enabled delivery of SDF1a at the ventral side of breast cancer cells reveals a crosstalk between cellular receptors to promote the invasive phenotype. Biomaterials, 127:61-74, 2017.
  4. Lubart Q et al., Role of phosphorylation in moesin interactions with PIP2-containing biomimetic membranes. Biophys. J. 114:98-112, 2018.
  5. Machillot P et al. Automated buildup of biomimetic in cell culture microplates for high throughput screening of cellular behaviors. Adv. Mat. July30(27). e1801097.
  6. Ho-Shui-Ling et al. Bone regeneration strategies: engineered scaffolds, biomolecules and stem cells. Current stage and future perspectives. Biomaterials. 180:143-162, 2018.
  7. Migliorini E et al. Practical guide to characterize biomolecules adsorption at solid surfaces. Biointerphases. 13:06D303. 2018
  8. Migliorini E et al. Learning from BMPs and their biophysical extracellular matrix microenvironment for biomaterial design. Bone. 2020 Dec;141:115540.
  9. Garot C, Bettega G & C. Picart. Additive manufacturing of material scaffolds for bone regeneration: toward application in the clinics. Advanced. Functional Materials. 2020. 31: 2006967.
  10. Sefkow-Werner et al. Heparan sulfate co-immobilized with cRGD ligands and BMP2 on biomimetic platforms promotes BMP2-mediated osteogenic differentiation. Acta Biomater. 2020 Sep 15;114:90-103.
  11. Khodr V. et al. High-throughput measurements of bone morphogenetic protein/bone morphogenetic protein receptor interactions using biolayer interferometry. Biointerphases. 2021 Jun 8;16(3):031001.
  12. Bouyer M., Garot C., et al. 3D-printed scaffolds combined to 2D osteoinductive coatings to repair critical-size bone defect. Materials Today Bio. 11:199113, 2021.
  13. Sales Ramos A et al. Differential bioactivity of four BMP-family members as function of biomaterial stiffness. Biomaterials. 2022 Feb;281:121363.