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Synthèse et propriétés de monocristaux, de poudres, films minces ou hétérostructures

Etudes à l'interface avec la matière biologique

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Associate Professor, HDR, Grenoble-INP Phelma Researcher @ LMGP, IMBM group (Interfaces between Materials and Biological Matter) Resp pédagogique Plateforme Biotechnologies du CIME Nanotech


  • Tél. : 04 56 52 93 35
  • Fax : 0456529301

  • Bureau 1 : M1-07
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Since 2006, I teach at the Grenoble Institute of Technology, Grenoble INP - Phelma at the Master I and II levels in the track Biomedical Engineering and in the International Master program “Nanotechnology”. I am in charge of the following subjects : Molecular Biology, Cell Biology, Immunology and Biochip technology.

Within the IMBM team, we are working at the interface between material science, biochemistry and cellular biology. My main research area is protein stability at interfaces.

Selected publications:

Nault L, et al (2013) Human insulin adsorption kinetics, conformational changes and amyloidal aggregate formation on hydrophobic surfaces. Acta Biomaterialia 9(2), 5070-5079.
Nault L, et al (2013) Peptides that form ?-sheets on hydrophobic surfaces accelerate surface-induced insulin amyloidal aggregation. FEBS Letters, 587, 1281–1286.
Chouchane K, et al  (2015) Dual effect of (LK)nL peptides on the onset of insulin amyloid fiber formation at hydrophobic surfaces. J Phys Chem B 119(30), 10543-10553
Frachon T, et al (2016) Insulin aggregation at a dynamic solid-liquid-air interface. Langmuir 32(49), 13009-13019.

Activités / CV

Born 10th July 1967 in Esch-sur-Alzette (Luxembourg)
Nationality : luxembourgish

Education at the Swiss Federal Institute of Technology (ETH) in Zurich
1986-1991     ETH Diploma in Natural Sciences (Microbiology, Genetics, Cell Biology,
                      Immunology, Plant Physiology)
1995               PhD in Natural Sciences

                      Thesis director : Prof. Dr. Hauke Hennecke
                      Subject: In the search for new NifA-dependent genes and their function in Bradyrhizobium japonicum
  Postdoctoctoral postions
1995 - 2002   at CEA-Grenoble (France)
2002 - 2006   at EMBL-Grenoble (France)

Since 2006, Associate professor, HDR, at Grenoble INP - Phelma (Molecular and Cell Biology, Immunology, Biosensors), where I am also in charge of  :
  • International Relations G-INP - Phelma Biomedical Engineering
Since 2008, I am responsible for international exchanges of students from and to Phelma in Biomedical Engineering. I am in charge of establishing contacts with partner universities in my field of expertise. I advise Phelma students for academic exchanges abroad and coordinate the stay of incoming exchange students at our university.
  • The Biotech facility at CIME Nanotech
Since 2006, I am co-responsible for the Biotech facility of the “Centre interuniversitaire de microélectonique et nanotechnologies” (CIME Nanotech). This facility is equipped with state-of-the-art techniques to isolate, purify and characterize nucleic acids and proteins as well as cultivating and imaging pro- and eukaryotic cells.  The facility hosts yearly an average of 6000 student-hours originating from different universities and educational programs.

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mise à jour le 11 décembre 2020

  • Tutelle CNRS
  • Tutelle Grenoble INP
Université Grenoble Alpes