PUBLICATIONS:
2014
27. Ramade A, Legant WR, Picart C, Chen CS, and Boudou T. Microfabrication of a platform to measure and manipulate the mechanics of engineered microtissues. Methods Cell Biol 121: 191–211, 2014
26. Wang H, Svoronos AA, Boudou T, Sakar MS, Schell JY, Morgan JR, Chen CS, Shenoy VB. Necking and failure of constrained 3D microtissues induced by cellular tension. PNAS 110: 20923-20928. 2014
2013
25. Monge C, Saha N, Boudou T, Pózos-Vásquez C, Dulong V, Glinel K, Picart C. Rigidity-patterned polyelectrolyte films to control myoblast cell adhesion and spatial organization. Adv. Funct. Mater. 23: 3432-3442, 2013
24. Caridade SG, Monge C, Gilde FD, Boudou T, Mano JF, Picart C. Free-standing polyelectrolyte membranes made of chitosan and alginate. Biomacromolecules 14: 1653-1660, 2013
23. Almodovar J, Crouzier T, Selimovic S, Boudou T, Khademhosseini A, Picart C. Gradients of physical and biochemical cues on polyelectrolyte multilayer films generated via microfluidics. Lab on a Chip 13:1562-1570, 2013
22. Zhao R, Boudou T, Wang W-G, Chen CS, Reich DH. Decoupling cell and matrix mechanics in engineered microtissues using magnetically actuated microcantilevers.Adv. Mater. 25:1699-1705, 2013
21. West AR, Zaman N, Cole DJ, Walker MJ, Legant WR, Boudou T, Chen CS, Favreau JT, Gaudette GR, Cowley EA, Maksym GN. Development and characterisation of a 3D multi-cell microtissue culture model of airway smooth muscle. AJP Lung Cell. Mol. Physiol. 304:L4-16, 2013
2012
20. Sakar MS, Neal D, Boudou T, Borochin MA, Li Y, Weiss R, Kamm RD, Chen CS, Asada HH. Formation and optogenetic control of engineered 3D skeletal muscle bioactuators. Lab Chip 12: 4976-4985, 2012
19. Boudou T, Kharkar P, Jing J, Guillot R, Pignot-Paintrand I, Auzely-Velty R, Picart C. Polyelectrolyte multilayer nanoshells with hydrophobic nanodomains for delivery of Paclitaxel. J. Controlled Release 159: 403-412, 2012
18. Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS. A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Eng. A 18: 910-919, 2012
2011
17. Eyckmans J, Boudou T, Yu X, Chen CS. A hitchhiker's guide to mechanobiology. Dev. Cell. 21: 35-47, 2011
16. Yamanlar S, Sant S, Boudou T, Picart C and Khademhosseini A. Surface functionalization of hyaluronic acid hydrogels by polyelectrolyte multilayer films. Biomaterials 32: 5590-99, 2011
15. Cui D, Jing J, Boudou T, Pignot-Paintrand I, De Koker S, De Geest BG, Picart C, Auzély-Velty R. Hydrophobic shell loading of biopolyelectrolyte capsules. Adv. Mater. 23: H200-4, 2011
14. Crouzier T, Fourel L, Boudou T, Albigès-Rizo C and Picart C. Presentation of BMP-2 from a soft biopolymeric film unveils its activity on cell adhesion and migration. Adv. Mat. 23: H111-8, 2011
13. Boudou T, Crouzier T, Nicolas C, Picart C. Boudou T, Crouzier T, Nicolas C, Ren K, Picart C. Polyelectrolyte multilayer nanofilms used as thin materials for cell mechano-sensitivity studies. Macromol. Biosci. 11: 77-89, 2011
2010
12. Crouzier T, Boudou T, Picart C. Polysaccharide-based polyelectrolyte multilayers. Curr. Opin. Colloid Interface Sci. 15: 417-426, 2010
11. Cui D, Szarpak A, Pignot-Paintrand I, Varrot A, Boudou T, Detrembleur C, Jerôme C, Picart C, Auzély-Velty R. Contact-killing polyelectrolyte microcapsules based on chitosan derivatives. Adv. Funct. Mat. 20: 3303-3312, 2010
10. Crouzier T, Szarpak A, Boudou T, Auzely-Velty R, Picart C. Polysaccharide blend multilayers containing hyaluronan and heparin as a delivery system for rhBMP-2. Small 6: 651-662, 2010
9. Boudou T, Crouzier C, Ren K, Blin G, Picart C. Multiple functionalities of polyelectrolyte multilayer films: New biomedical applications. Adv. Mater. 22: 441-467, 2010
2009
8. Kadi S, Cui D, Bayma E, Boudou T, Nicolas C, Glinel K, Picart C, Auzly-Velty R. Alkylamino hydrazide derivatives of hyaluronic acid: Synthesis, characterization in semidilute aqueous solutions, and assembly into thin multilayer films. Biomacromolecules 10: 2875-84, 2009
7. Pozos-Vázquez C, Boudou T, Dulong V, Nicolas C, Picart C, Glinel K. Variation of polyelectrolyte film stiffness by photo-cross-linking: A new way to control cell adhesion. Langmuir 25: 3556-63, 2009
6. Boudou T, Crouzier C, Auzély-Velty R, Glinel K, Picart C. Internal composition versus the mechanical properties of polyelectrolyte multilayer films: the influence of chemical cross-linking. Langmuir 25: 13809-19, 2009
5. Schiavone P, Chassat F, Boudou T, Promayon E, Valdivia F, Payan Y. In vivo measurement of human brain elasticity using a light aspiration device. Med. Image Anal. 13: 673-8, 2009
4. Boudou T, Ohayon J, Picart C, Pettigrew RI, Tracqui P. Nonlinear elastic properties of polyacrylamide gels: implications for quantification of cellular forces. Biorheology 46: 191-205, 2009
2008
3. Tracqui P, Ohayon J, Boudou T. Theoretical analysis of the adaptative contractile behaviour of a single cardiomyocyte cultured on elastic substrates with varying stiffness. J. Theor. Biol. 255: 92-105, 2008
2006
2. Boudou T, Ohayon J, Picart C, Tracqui P. An extended relationship for the characterization of Young's modulus and Poisson's ratio of tunable polyacrylamide gels. Biorheology 43: 721-8, 2006
1. Boudou T, Ohayon J, Arntz Y, Finet G, Picart C, Tracqui P. An extended modeling of the micropipette aspiration experiment for the characterization of the Young's modulus and Poisson's ratio of adherent thin biological samples: Numerical and experimental studies. J. Biomech. 39: 1677-85, 2006
2014
27. Ramade A, Legant WR, Picart C, Chen CS, and Boudou T. Microfabrication of a platform to measure and manipulate the mechanics of engineered microtissues. Methods Cell Biol 121: 191–211, 2014
26. Wang H, Svoronos AA, Boudou T, Sakar MS, Schell JY, Morgan JR, Chen CS, Shenoy VB. Necking and failure of constrained 3D microtissues induced by cellular tension. PNAS 110: 20923-20928. 2014
2013
25. Monge C, Saha N, Boudou T, Pózos-Vásquez C, Dulong V, Glinel K, Picart C. Rigidity-patterned polyelectrolyte films to control myoblast cell adhesion and spatial organization. Adv. Funct. Mater. 23: 3432-3442, 2013
24. Caridade SG, Monge C, Gilde FD, Boudou T, Mano JF, Picart C. Free-standing polyelectrolyte membranes made of chitosan and alginate. Biomacromolecules 14: 1653-1660, 2013
23. Almodovar J, Crouzier T, Selimovic S, Boudou T, Khademhosseini A, Picart C. Gradients of physical and biochemical cues on polyelectrolyte multilayer films generated via microfluidics. Lab on a Chip 13:1562-1570, 2013
22. Zhao R, Boudou T, Wang W-G, Chen CS, Reich DH. Decoupling cell and matrix mechanics in engineered microtissues using magnetically actuated microcantilevers.Adv. Mater. 25:1699-1705, 2013
21. West AR, Zaman N, Cole DJ, Walker MJ, Legant WR, Boudou T, Chen CS, Favreau JT, Gaudette GR, Cowley EA, Maksym GN. Development and characterisation of a 3D multi-cell microtissue culture model of airway smooth muscle. AJP Lung Cell. Mol. Physiol. 304:L4-16, 2013
2012
20. Sakar MS, Neal D, Boudou T, Borochin MA, Li Y, Weiss R, Kamm RD, Chen CS, Asada HH. Formation and optogenetic control of engineered 3D skeletal muscle bioactuators. Lab Chip 12: 4976-4985, 2012
19. Boudou T, Kharkar P, Jing J, Guillot R, Pignot-Paintrand I, Auzely-Velty R, Picart C. Polyelectrolyte multilayer nanoshells with hydrophobic nanodomains for delivery of Paclitaxel. J. Controlled Release 159: 403-412, 2012
18. Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS. A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Eng. A 18: 910-919, 2012
2011
17. Eyckmans J, Boudou T, Yu X, Chen CS. A hitchhiker's guide to mechanobiology. Dev. Cell. 21: 35-47, 2011
16. Yamanlar S, Sant S, Boudou T, Picart C and Khademhosseini A. Surface functionalization of hyaluronic acid hydrogels by polyelectrolyte multilayer films. Biomaterials 32: 5590-99, 2011
15. Cui D, Jing J, Boudou T, Pignot-Paintrand I, De Koker S, De Geest BG, Picart C, Auzély-Velty R. Hydrophobic shell loading of biopolyelectrolyte capsules. Adv. Mater. 23: H200-4, 2011
14. Crouzier T, Fourel L, Boudou T, Albigès-Rizo C and Picart C. Presentation of BMP-2 from a soft biopolymeric film unveils its activity on cell adhesion and migration. Adv. Mat. 23: H111-8, 2011
13. Boudou T, Crouzier T, Nicolas C, Picart C. Boudou T, Crouzier T, Nicolas C, Ren K, Picart C. Polyelectrolyte multilayer nanofilms used as thin materials for cell mechano-sensitivity studies. Macromol. Biosci. 11: 77-89, 2011
2010
12. Crouzier T, Boudou T, Picart C. Polysaccharide-based polyelectrolyte multilayers. Curr. Opin. Colloid Interface Sci. 15: 417-426, 2010
11. Cui D, Szarpak A, Pignot-Paintrand I, Varrot A, Boudou T, Detrembleur C, Jerôme C, Picart C, Auzély-Velty R. Contact-killing polyelectrolyte microcapsules based on chitosan derivatives. Adv. Funct. Mat. 20: 3303-3312, 2010
10. Crouzier T, Szarpak A, Boudou T, Auzely-Velty R, Picart C. Polysaccharide blend multilayers containing hyaluronan and heparin as a delivery system for rhBMP-2. Small 6: 651-662, 2010
9. Boudou T, Crouzier C, Ren K, Blin G, Picart C. Multiple functionalities of polyelectrolyte multilayer films: New biomedical applications. Adv. Mater. 22: 441-467, 2010
2009
8. Kadi S, Cui D, Bayma E, Boudou T, Nicolas C, Glinel K, Picart C, Auzly-Velty R. Alkylamino hydrazide derivatives of hyaluronic acid: Synthesis, characterization in semidilute aqueous solutions, and assembly into thin multilayer films. Biomacromolecules 10: 2875-84, 2009
7. Pozos-Vázquez C, Boudou T, Dulong V, Nicolas C, Picart C, Glinel K. Variation of polyelectrolyte film stiffness by photo-cross-linking: A new way to control cell adhesion. Langmuir 25: 3556-63, 2009
6. Boudou T, Crouzier C, Auzély-Velty R, Glinel K, Picart C. Internal composition versus the mechanical properties of polyelectrolyte multilayer films: the influence of chemical cross-linking. Langmuir 25: 13809-19, 2009
5. Schiavone P, Chassat F, Boudou T, Promayon E, Valdivia F, Payan Y. In vivo measurement of human brain elasticity using a light aspiration device. Med. Image Anal. 13: 673-8, 2009
4. Boudou T, Ohayon J, Picart C, Pettigrew RI, Tracqui P. Nonlinear elastic properties of polyacrylamide gels: implications for quantification of cellular forces. Biorheology 46: 191-205, 2009
2008
3. Tracqui P, Ohayon J, Boudou T. Theoretical analysis of the adaptative contractile behaviour of a single cardiomyocyte cultured on elastic substrates with varying stiffness. J. Theor. Biol. 255: 92-105, 2008
2006
2. Boudou T, Ohayon J, Picart C, Tracqui P. An extended relationship for the characterization of Young's modulus and Poisson's ratio of tunable polyacrylamide gels. Biorheology 43: 721-8, 2006
1. Boudou T, Ohayon J, Arntz Y, Finet G, Picart C, Tracqui P. An extended modeling of the micropipette aspiration experiment for the characterization of the Young's modulus and Poisson's ratio of adherent thin biological samples: Numerical and experimental studies. J. Biomech. 39: 1677-85, 2006
Taxol-loaded microcapsules on a breast cancer cell (MDA-MB 231)
C2C12 myoblasts aligned on rigidity lines
C2C12 myoblasts spreding on PEM films
FE Modeling of cardiomyocyte contraction
Brain pipette aspiration experiment
A 600µm microtissue made of collagen and fibroblasts
FE modeling of micropipette aspiration