1/ For label-free field effect based DNA detection, we develop highly stable semiconductors as an alternative to the usual Si substrate. Our expertise in elaboration and functionalization of materials enables us to produce semiconductive nanostructures with a high surface/volume ratio to enhance the biosensor sensitivity. Typicallly :
SnO2 vertical nanowire forests and nanoporous films,
SiC nanowire field effect transistor (NWFET),
Nanonets : network of randomly oriented Si and ZnO nanowires
2/ Direct detection of bacteria is a challenge. We have investigated the specific electrochemical signal of bacteria (E. coli K12 strains) incubated in anaerobic condition on biased ITO film.
3/ Coupling the electrochemical detection with magnetic capture Micromagnets are combined with nanoparticles and surface electrodes to develop rapid and portable diagnostic sensors.